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Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

Chaperone-mediated autophagy (CMA) ensures the selective degradation of cellular proteins endowed with a KFERQ-like motif by lysosomes. It is estimated that 30% of all cellular proteins can be directed to the lysosome for CMA degradation, but only a few substrates have been formally identified so fa...

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Bibliographic Details
Published in:Cells
Main Authors: Robert, Guillaume, Jacquel, Arnaud, Auberger, Patrick
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830112/
https://ncbi.nlm.nih.gov/pubmed/31623164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101260
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