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Chaperone-mediated autophagy: roles in disease and aging

This review focuses on chaperone-mediated autophagy (CMA), one of the proteolytic systems that contributes to degradation of intracellular proteins in lysosomes. CMA substrate proteins are selectively targeted to lysosomes and translocated into the lysosomal lumen through the coordinated action of c...

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Bibliografiske detaljer
Main Authors: Cuervo, Ana Maria, Wong, Esther
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879702/
https://ncbi.nlm.nih.gov/pubmed/24281265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.153
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