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Chaperone-mediated autophagy: roles in disease and aging

This review focuses on chaperone-mediated autophagy (CMA), one of the proteolytic systems that contributes to degradation of intracellular proteins in lysosomes. CMA substrate proteins are selectively targeted to lysosomes and translocated into the lysosomal lumen through the coordinated action of c...

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Detalhes bibliográficos
Main Authors: Cuervo, Ana Maria, Wong, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879702/
https://ncbi.nlm.nih.gov/pubmed/24281265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.153
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