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Chaperone-mediated autophagy: roles in disease and aging

This review focuses on chaperone-mediated autophagy (CMA), one of the proteolytic systems that contributes to degradation of intracellular proteins in lysosomes. CMA substrate proteins are selectively targeted to lysosomes and translocated into the lysosomal lumen through the coordinated action of c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cuervo, Ana Maria, Wong, Esther
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879702/
https://ncbi.nlm.nih.gov/pubmed/24281265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.153
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