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Chaperone-mediated autophagy: roles in neurodegeneration

Chaperone-mediated autophagy (CMA) selectively delivers cytosolic proteins with an exposed CMA-targeting motif to lysosomes for degradation and plays an important role in protein quality control and cellular homeostasis. A growing body of evidence supports the hypothesis that CMA dysfunction may be...

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Detalhes bibliográficos
Main Authors: Wang, Gang, Mao, Zixu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177711/
https://ncbi.nlm.nih.gov/pubmed/25276349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-3-20
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