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Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration
Chaperone-mediated autophagy (CMA) contributes to selective degradation of individual soluble proteins in lysosomes. Unique to this type of autophagy is the fact that proteins reach the lysosomal lumen for degradation by directly crossing the lysosomal membrane, in contrast with the vesicle-mediated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998583/ https://ncbi.nlm.nih.gov/pubmed/20643207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.006 |
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