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Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration

Chaperone-mediated autophagy (CMA) contributes to selective degradation of individual soluble proteins in lysosomes. Unique to this type of autophagy is the fact that proteins reach the lysosomal lumen for degradation by directly crossing the lysosomal membrane, in contrast with the vesicle-mediated...

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Bibliografski detalji
Glavni autori: Koga, Hiroshi, Cuervo, Ana Maria
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998583/
https://ncbi.nlm.nih.gov/pubmed/20643207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.006
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