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Constitutive Upregulation of Chaperone-Mediated Autophagy in Huntington's Disease
Autophagy contributes to the removal of prone-to-aggregate proteins, but in several instances these pathogenic proteins have been shown to interfere with autophagic activity. In the case of Huntington's disease (HD), a congenital neurodegenerative disorder resulting from mutation in the hunting...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282924/ https://ncbi.nlm.nih.gov/pubmed/22171050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3219-11.2011 |
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