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Constitutive Upregulation of Chaperone-Mediated Autophagy in Huntington's Disease

Autophagy contributes to the removal of prone-to-aggregate proteins, but in several instances these pathogenic proteins have been shown to interfere with autophagic activity. In the case of Huntington's disease (HD), a congenital neurodegenerative disorder resulting from mutation in the hunting...

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Detalhes bibliográficos
Main Authors: Koga, Hiroshi, Martinez-Vicente, Marta, Arias, Esperanza, Kaushik, Susmita, Sulzer, David, Cuervo, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282924/
https://ncbi.nlm.nih.gov/pubmed/22171050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3219-11.2011
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