Caspase Activation Is Required for Terminal Erythroid Differentiation

The cysteine proteases known as caspases play a central role in most apoptotic pathways. Here, we show that caspase inhibitors arrest the maturation of human erythroid progenitors at early stages of differentiation, before nucleus and chromatin condensation. Effector caspases such as caspase-3 are t...

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Detalhes bibliográficos
Main Authors: Zermati, Yael, Garrido, Carmen, Amsellem, Sophie, Fishelson, Serge, Bouscary, Didier, Valensi, Françoise, Varet, Bruno, Solary, Eric, Hermine, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193347/
https://ncbi.nlm.nih.gov/pubmed/11208865
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