Caspase Activation Is Required for Terminal Erythroid Differentiation

The cysteine proteases known as caspases play a central role in most apoptotic pathways. Here, we show that caspase inhibitors arrest the maturation of human erythroid progenitors at early stages of differentiation, before nucleus and chromatin condensation. Effector caspases such as caspase-3 are t...

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Autori principali: Zermati, Yael, Garrido, Carmen, Amsellem, Sophie, Fishelson, Serge, Bouscary, Didier, Valensi, Françoise, Varet, Bruno, Solary, Eric, Hermine, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
Soggetti:
Brief Definitive Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193347/
https://ncbi.nlm.nih.gov/pubmed/11208865
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