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Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling
Stem cell factor (SCF) and erythropoietin are strictly required for preventing apoptosis and stimulating proliferation, allowing the differentiation of erythroid precursors from colony-forming unit-E to the polychromatophilic stage. In contrast, terminal maturation to generate reticulocytes occurs i...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131901/ https://ncbi.nlm.nih.gov/pubmed/21072057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.140 |
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