Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling

Stem cell factor (SCF) and erythropoietin are strictly required for preventing apoptosis and stimulating proliferation, allowing the differentiation of erythroid precursors from colony-forming unit-E to the polychromatophilic stage. In contrast, terminal maturation to generate reticulocytes occurs i...

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Bibliographische Detailangaben
Hauptverfasser: Gabet, A-S, Coulon, S, Fricot, A, Vandekerckhove, J, Chang, Y, Ribeil, J-A, Lordier, L, Zermati, Y, Asnafi, V, Belaid, Z, Debili, N, Vainchenker, W, Varet, B, Hermine, O, Courtois, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131901/
https://ncbi.nlm.nih.gov/pubmed/21072057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.140
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