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Nasal Administration of Cholera Toxin as a Mucosal Adjuvant Damages the Olfactory System in Mice
Cholera toxin (CT) induces severe diarrhea in humans but acts as an adjuvant to enhance immune responses to vaccines when administered orally. Nasally administered CT also acts as an adjuvant, but CT and CT derivatives, including the B subunit of CT (CTB), are taken up from the olfactory epithelium...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589288/ https://ncbi.nlm.nih.gov/pubmed/26422280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139368 |
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