A Novel Combined Adjuvant For Nasal Delivery Elicits Mucosal Immunity To Influenza In Aging

Since a combination of flt3 ligand plasmid (pFL) and CpG-oligodeoxynucleotides (ODN)(3) as a dendritic cell (DC)-targeting double mucosal adjuvant elicited ovalbumin-specific secretory IgA (S-IgA) antibody (Ab) responses, we examined whether this double adjuvant could induce influenza-specific prote...

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Detalhes bibliográficos
Main Authors: Asanuma, Hideki, Zamri, Normaiza Binti, Sekine, Shin-ichi, Fukuyama, Yoshiko, Tokuhara, Daisuke, Gilbert, Rebekah S., Fukuiwa, Tatsuya, Sata, Tetsutaro, Tashiro, Masato, Fujihashi, Kohtaro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253905/
https://ncbi.nlm.nih.gov/pubmed/22100889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.10.093
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