Notch-Ligand Expression By NALT Dendritic Cells Regulates Mucosal Th1- and Th2-Type Responses(1)

Our previous studies showed that an adenovirus (Ad) serotype 5 vector expressing Flt3 ligand (Ad-FL) as nasal adjuvant activates CD11c(+) dendritic cells (DCs) for the enhancement of antigen (Ag)-specific IgA antibody (Ab) responses. In this study, we examined the molecular mechanism for activation...

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Autores principales: Fukuyama, Yoshiko, Tokuhara, Daisuke, Sekine, Shinichi, Kataoka, Kosuke, Markham, Jonathan D., Irwin, Allyson R., Moon, Grace H., Tokuhara, Yuka, Fujihashi, Keiko, Davydova, Julia, Yamamoto, Masato, Gilbert, Rebekah S., Fujihashi, Kohtaro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273652/
https://ncbi.nlm.nih.gov/pubmed/22200492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.12.046
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