Oral-Nasopharyngeal Dendritic Cells Mediate T Cell-Independent IgA Class Switching on B-1 B Cells

Native cholera toxin (nCT) as a nasal adjuvant was shown to elicit increased levels of T-independent S-IgA antibody (Ab) responses through IL-5- IL-5 receptor interactions between CD4(+) T cells and IgA(+) B-1 B cells in murine submandibular glands (SMGs) and nasal passages (NPs). Here, we further i...

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Main Authors: Kataoka, Kosuke, Fujihashi, Keiko, Terao, Yutaka, Gilbert, Rebekah S., Sekine, Shinichi, Kobayashi, Ryoki, Fukuyama, Yoshiko, Kawabata, Shigetada, Fujihashi, Kohtaro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183055/
https://ncbi.nlm.nih.gov/pubmed/21980444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025396
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