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Functional Transforming Growth Factor-β Receptor Type II Expression by CD4(+) T Cells in Peyer's Patches Is Essential for Oral Tolerance Induction

Our previous studies have shown that Peyer's patches (PPs) play a key role in the induction of oral tolerance. Therefore, we hypothesized that PPs are an important site for Transforming Growth Factor (TGF)- β signaling and sought to prove that this tissue is of importance in oral tolerance indu...

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Detalhes bibliográficos
Main Authors: Gilbert, Rebekah S., Kobayashi, Ryoki, Sekine, Shinichi, Fujihashi, Kohtaro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210179/
https://ncbi.nlm.nih.gov/pubmed/22087328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027501
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