Ovalbumin-Protein σ1 M Cell Targeting Facilitates Oral Tolerance with Reduction of Antigen-Specific CD4(+) T Cells

BACKGROUND & AIMS: The follicle associated epithelium (FAE) plays key roles in antigen uptake and subsequent induction of mucosal immunity. In this study, we examined whether M cell targeting using a protein antigen (Ag) delivery system would induce oral tolerance instead of enhancement of Ag-sp...

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Auteurs principaux: Suzuki, Hideaki, Sekine, Shinichi, Kataoka, Kosuke, Pascual, David W., Maddaloni, Massimo, Kobayashi, Ryoki, Fujhashi, Keiko, Kozono, Haruo, McGhee, Jerry R., Fujihashi, Kohtaro
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579966/
https://ncbi.nlm.nih.gov/pubmed/18565333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.05.037
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