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Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response
DNA double-strand break repair involves phosphorylation of histone variant H2AX (‘γH2AX’), which accumulates in foci at sites of damage. In current models, the recruitment of multiple DNA repair proteins to γH2AX foci depends mainly on recognition of this ‘mark’ by a single protein, MDC1. However, D...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589150/ https://ncbi.nlm.nih.gov/pubmed/26344695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1908 |
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