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Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function
The formation of cellular microtubule networks is regulated by the γ-tubulin ring complex (γ-TuRC). This ∼2.3 MD assembly of >31 proteins includes γ-tubulin and GCP2-6, as well as MZT1 and an actin-like protein in a “lumenal bridge” (LB). The challenge of reconstituting the γ-TuRC has limited dis...
Gespeichert in:
| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7844428/ https://ncbi.nlm.nih.gov/pubmed/33496729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009146 |
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