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Molecular insight into how γ-TuRC makes microtubules

As one of four filament types, microtubules are a core component of the cytoskeleton and are essential for cell function. Yet how microtubules are nucleated from their building blocks, the αβ-tubulin heterodimer, has remained a fundamental open question since the discovery of tubulin 50 years ago. R...

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Pubblicato in:J Cell Sci
Autori principali: Thawani, Akanksha, Petry, Sabine
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325954/
https://ncbi.nlm.nih.gov/pubmed/34297125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.245464
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