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The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy
Determining how microtubules (MTs) are nucleated is essential for understanding how the cytoskeleton assembles. While the MT nucleator, γ-tubulin ring complex (γ-TuRC) has been identified, precisely how γ-TuRC nucleates a MT remains poorly understood. Here, we developed a single molecule assay to di...
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| Publicado no: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7338055/ https://ncbi.nlm.nih.gov/pubmed/32538784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54253 |
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