Radiosensitivity in breast cancer assessed by the histone γ-H2AX and 53BP1 foci

BACKGROUND: High expression of constitutive histone γ-H2AX, a sensitive marker of DNA damage, might be indicative of defective DNA repair pathway or genomic instability. 53BP1 (p53-binding protein 1) is a conserved checkpoint protein with properties of a DNA double-strand breaks sensor. This study e...

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Bibliographic Details
Main Authors: Djuzenova, Cholpon S, Elsner, Ines, Katzer, Astrid, Worschech, Eike, Distel, Luitpold V, Flentje, Michael, Polat, Bülent
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653697/
https://ncbi.nlm.nih.gov/pubmed/23617930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-8-98
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