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Radiosensitivity in breast cancer assessed by the histone γ-H2AX and 53BP1 foci
BACKGROUND: High expression of constitutive histone γ-H2AX, a sensitive marker of DNA damage, might be indicative of defective DNA repair pathway or genomic instability. 53BP1 (p53-binding protein 1) is a conserved checkpoint protein with properties of a DNA double-strand breaks sensor. This study e...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653697/ https://ncbi.nlm.nih.gov/pubmed/23617930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-8-98 |
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