Hsp90 Inhibitors NVP-AUY922 and NVP-BEP800 May Exert a Significant Radiosensitization on Tumor Cells along with a Cell Type-Specific Cytotoxicity

Targeting heat shock protein 90 (Hsp90) provides a promising therapeutic approach to enhance the sensitivity of tumor cells to ionizing radiation (IR). To explore the impact of scheduling drug-IR administration, in the present study, we analyzed the response of lung carcinoma A549 and glioblastoma S...

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Bibliografiske detaljer
Main Authors: Niewidok, Natalia, Wack, Linda-Jacqueline, Schiessl, Sarah, Stingl, Lavinia, Katzer, Astrid, Polat, Bülent, Sukhorukov, Vladimir L, Flentje, Michael, Djuzenova, Cholpon S
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470116/
https://ncbi.nlm.nih.gov/pubmed/23066444
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