Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells

Outcomes for poor-risk localized prostate cancers treated with radiation are still insufficient. Targeting the “non-oncogene” addiction or stress response machinery is an appealing strategy for cancer therapeutics. Heat-shock-protein-90 (Hsp90), an integral member of this machinery, is a molecular c...

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Detalhes bibliográficos
Main Authors: Gandhi, Nishant, Wild, Aaron T., Chettiar, Sivarajan T., Aziz, Khaled, Kato, Yoshinori, Gajula, Rajendra P., Williams, Russell D., Cades, Jessica A., Annadanam, Anvesh, Song, Danny, Zhang, Yonggang, Hales, Russell K., Herman, Joseph M., Armour, Elwood, DeWeese, Theodore L., Schaeffer, Edward M., Tran, Phuoc T.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667875/
https://ncbi.nlm.nih.gov/pubmed/23358469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23626
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