Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells

Outcomes for poor-risk localized prostate cancers treated with radiation are still insufficient. Targeting the “non-oncogene” addiction or stress response machinery is an appealing strategy for cancer therapeutics. Heat-shock-protein-90 (Hsp90), an integral member of this machinery, is a molecular c...

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Auteurs principaux: Gandhi, Nishant, Wild, Aaron T., Chettiar, Sivarajan T., Aziz, Khaled, Kato, Yoshinori, Gajula, Rajendra P., Williams, Russell D., Cades, Jessica A., Annadanam, Anvesh, Song, Danny, Zhang, Yonggang, Hales, Russell K., Herman, Joseph M., Armour, Elwood, DeWeese, Theodore L., Schaeffer, Edward M., Tran, Phuoc T.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667875/
https://ncbi.nlm.nih.gov/pubmed/23358469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23626
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