Hedgehog Pathway Inhibition Radiosensitizes Non-Small Cell Lung Cancers

PURPOSE: Despite improvements in chemoradiation, local control remains a major clinical problem in locally advanced non-small cell lung cancer. The Hedgehog pathway has been implicated in tumor recurrence by promoting survival of tumorigenic precursors and through effects on tumor-associated stroma....

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Main Authors: Zeng, Jing, Aziz, Khaled, Chettiar, Sivarajan T., Aftab, Blake T., Armour, Michael, Gajula, Rajendra, Gandhi, Nishant, Salih, Tarek, Herman, Joseph M., Wong, John, Rudin, Charles M., Tran, Phuoc T., Hales, Russell K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145860/
https://ncbi.nlm.nih.gov/pubmed/23182391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.10.014
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