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Assessing ‘Radiosensitivity’ with kinetic profiles of γ-H2AX, 53BP1 and BRCA1 Foci
BACKGROUND AND PURPOSE: DNA repair assays to identify radiosensitive patients have had limited clinical implementation due to long turn-around times or limited specificity. This study evaluates γ-H2AX Irradiation Induced Foci (IRIF) kinetics as a more rapid surrogate for the ‘gold standard’ colony s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202034/ https://ncbi.nlm.nih.gov/pubmed/21722985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2011.05.065 |
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