A prospective study on histone γ-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome

BACKGROUND: The prognostic value of histone γ-H2AX and 53BP1 proteins to predict the radiotherapy (RT) outcome of patients with rectal carcinoma (RC) was evaluated in a prospective study. High expression of the constitutive histone γ-H2AX is indicative of defective DNA repair pathway and/or genomic...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Djuzenova, Cholpon S., Zimmermann, Marcus, Katzer, Astrid, Fiedler, Vanessa, Distel, Luitpold V., Gasser, Martin, Waaga-Gasser, Anna-Maria, Flentje, Michael, Polat, Bülent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635621/
https://ncbi.nlm.nih.gov/pubmed/26541290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1890-9
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