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Multi-Facial, Non-Peptidic α-Helix Mimetics

α-Helices often recognize their target proteins at protein–protein interfaces through more than one recognition face. This review describes the state-of-the-art in the design of non-peptidic α-helix mimetics that reproduce functionality from multiple faces of an α-helix.

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Lanning, Maryanna E., Fletcher, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588149/
https://ncbi.nlm.nih.gov/pubmed/26404384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology4030540
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