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Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env
The HIV-1 envelope (Env) spike contains limited epitopes for broadly neutralizing antibodies (bNAbs); thus, most neutralizing antibodies are strain specific. The 8ANC195 epitope, defined by crystal and electron microscopy (EM) structures of bNAb 8ANC195 complexed with monomeric gp120 and trimeric En...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587768/ https://ncbi.nlm.nih.gov/pubmed/26359989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.035 |
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