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Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
Broadly neutralizing antibodies (bNAbs) against HIV-1 envelope (Env) inform vaccine design and are potential therapeutic agents. We identified SF12 and related bNAbs with up to 62% neutralization breadth from an HIV-infected donor. SF12 recognized a glycan-dominated epitope on Env’s silent face and...
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| Veröffentlicht in: | Immunity |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591006/ https://ncbi.nlm.nih.gov/pubmed/31126879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.04.014 |
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