BioID-based Identification of Skp Cullin F-box (SCF)(β-TrCP1/2) E3 Ligase Substrates

The identification of ubiquitin E3 ligase substrates has been challenging, due in part to low-affinity, transient interactions, the rapid degradation of targets and the inability to identify proteins from poorly soluble cellular compartments. SCF(β-TrCP1) and SCF(β-TrCP2) are well-studied ubiquitin...

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Foilsithe in:Mol Cell Proteomics
Main Authors: Coyaud, Etienne, Mis, Monika, Laurent, Estelle M. N., Dunham, Wade H., Couzens, Amber L., Robitaille, Melanie, Gingras, Anne-Claude, Angers, Stephane, Raught, Brian
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587326/
https://ncbi.nlm.nih.gov/pubmed/25900982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.045658
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