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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers

Our knowledge about the clonal composition and intraclonal diversity of the human memory B-cell compartment and the relationship between memory B-cell subsets is still limited, although these are central issues for our understanding of adaptive immunity. We performed a deep sequencing analysis of re...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Budeus, Bettina, Schweigle de Reynoso, Stefanie, Przekopowitz, Martina, Hoffmann, Daniel, Seifert, Marc, Küppers, Ralf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586852/
https://ncbi.nlm.nih.gov/pubmed/26324941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511270112
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