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Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centers
Our knowledge about the clonal composition and intraclonal diversity of the human memory B-cell compartment and the relationship between memory B-cell subsets is still limited, although these are central issues for our understanding of adaptive immunity. We performed a deep sequencing analysis of re...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586852/ https://ncbi.nlm.nih.gov/pubmed/26324941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511270112 |
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