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A chimeric prokaryotic pentameric ligand–gated channel reveals distinct pathways of activation
Recent high resolution structures of several pentameric ligand–gated ion channels have provided unprecedented details of their molecular architecture. However, the conformational dynamics and structural rearrangements that underlie gating and allosteric modulation remain poorly understood. We used a...
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| Publicado en: | J Gen Physiol |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586589/ https://ncbi.nlm.nih.gov/pubmed/26415570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511478 |
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