A chimeric prokaryotic pentameric ligand–gated channel reveals distinct pathways of activation

Recent high resolution structures of several pentameric ligand–gated ion channels have provided unprecedented details of their molecular architecture. However, the conformational dynamics and structural rearrangements that underlie gating and allosteric modulation remain poorly understood. We used a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Gen Physiol
Autori principali: Schmandt, Nicolaus, Velisetty, Phanindra, Chalamalasetti, Sreevatsa V., Stein, Richard A., Bonner, Ross, Talley, Lauren, Parker, Mark D., Mchaourab, Hassane S., Yee, Vivien C., Lodowski, David T., Chakrapani, Sudha
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586589/
https://ncbi.nlm.nih.gov/pubmed/26415570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511478
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi