טוען...
Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel
Desensitization in pentameric ligand-gated ion channels plays an important role in regulating neuronal excitability. Here, we show that docosahexaenoic acid (DHA), a key ω−3 polyunsaturated fatty acid in synaptic membranes, enhances the agonist-induced transition to the desensitized state in the pro...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378477/ https://ncbi.nlm.nih.gov/pubmed/28262093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23886 |
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