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The dual‐gate model for pentameric ligand‐gated ion channels activation and desensitization
Pentameric ligand‐gated ion channels (pLGICs) mediate fast neurotransmission in the nervous system. Their dysfunction is associated with psychiatric, neurological and neurodegenerative disorders such as schizophrenia, epilepsy and Alzheimer's disease. Understanding their biophysical and pharmac...
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| Publicado en: | J Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5978336/ https://ncbi.nlm.nih.gov/pubmed/29484660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275100 |
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