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The dual‐gate model for pentameric ligand‐gated ion channels activation and desensitization

Pentameric ligand‐gated ion channels (pLGICs) mediate fast neurotransmission in the nervous system. Their dysfunction is associated with psychiatric, neurological and neurodegenerative disorders such as schizophrenia, epilepsy and Alzheimer's disease. Understanding their biophysical and pharmac...

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Podrobná bibliografie
Vydáno v:J Physiol
Hlavní autoři: Gielen, Marc, Corringer, Pierre‐Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978336/
https://ncbi.nlm.nih.gov/pubmed/29484660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275100
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