A chimeric prokaryotic pentameric ligand–gated channel reveals distinct pathways of activation

Recent high resolution structures of several pentameric ligand–gated ion channels have provided unprecedented details of their molecular architecture. However, the conformational dynamics and structural rearrangements that underlie gating and allosteric modulation remain poorly understood. We used a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Gen Physiol
Hauptverfasser: Schmandt, Nicolaus, Velisetty, Phanindra, Chalamalasetti, Sreevatsa V., Stein, Richard A., Bonner, Ross, Talley, Lauren, Parker, Mark D., Mchaourab, Hassane S., Yee, Vivien C., Lodowski, David T., Chakrapani, Sudha
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586589/
https://ncbi.nlm.nih.gov/pubmed/26415570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511478
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge