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A chimeric prokaryotic pentameric ligand–gated channel reveals distinct pathways of activation
Recent high resolution structures of several pentameric ligand–gated ion channels have provided unprecedented details of their molecular architecture. However, the conformational dynamics and structural rearrangements that underlie gating and allosteric modulation remain poorly understood. We used a...
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| 出版年: | J Gen Physiol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586589/ https://ncbi.nlm.nih.gov/pubmed/26415570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511478 |
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