Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal

Cockayne syndrome complementation group B (CSB) protein is engaged in transcription-coupled repair (TCR) of UV induced DNA damage and its deficiency leads to progressive multisystem degeneration and premature aging. Here, we show that human CSB-deficient cells are hypersensitive to physiological con...

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Publicat a:Mutat Res
Autors principals: Maddukuri, Leena, Speina, Elżbieta, Christiansen, Mette, Dudzińska, Dominika, Zaim, Jolanta, Obtułowicz, Tomasz, Kabaczyk, Sylwia, Komisarski, Marek, Bukowy, Zuzanna, Szczegielniak, Jadwiga, Wójcik, Andrzej, Kuśmierek, Jaroslaw T., Stevnsner, Tinna, Bohr, Vilhelm A., Tudek, Barbara
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586250/
https://ncbi.nlm.nih.gov/pubmed/19481676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.03.007
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