ロード中...
Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes
[Image: see text] Multipolar interactions involving fluorine and the protein backbone have been frequently observed in protein–ligand complexes. Such fluorine–backbone interactions may substantially contribute to the high affinity of small molecule inhibitors. Here we found that introduction of trif...
保存先:
| 出版年: | J Med Chem |
|---|---|
| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2015
|
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4584387/ https://ncbi.nlm.nih.gov/pubmed/26288158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00975 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|