טוען...
Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction
[Image: see text] CDC25 phosphatases are key cell cycle regulators and represent very attractive but challenging targets for anticancer drug discovery. Here, we explored whether fragment-based screening represents a valid approach to identify inhibitors of CDC25B. This resulted in identification of...
שמור ב:
| הוצא לאור ב: | ACS Chem Biol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2014
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340349/ https://ncbi.nlm.nih.gov/pubmed/25423142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500883h |
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