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Structural insights into ligand recognition and selectivity for class A, B, and C GPCRs

The G protein-coupled receptor (GPCR) superfamily constitutes the largest collection of cell surface signaling proteins with approximately 800 members in the human genome. GPCRs regulate virtually all aspects of physiology and they are an important class of drug targets with ~30% of drugs on the mar...

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Dades bibliogràfiques
Publicat a:Eur J Pharmacol
Autors principals: Lee, Sang-Min, Booe, Jason M., Pioszak, Augen A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584177/
https://ncbi.nlm.nih.gov/pubmed/25981303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2015.05.013
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