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Structural insights into ligand recognition and selectivity for class A, B, and C GPCRs

The G protein-coupled receptor (GPCR) superfamily constitutes the largest collection of cell surface signaling proteins with approximately 800 members in the human genome. GPCRs regulate virtually all aspects of physiology and they are an important class of drug targets with ~30% of drugs on the mar...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Lee, Sang-Min, Booe, Jason M., Pioszak, Augen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584177/
https://ncbi.nlm.nih.gov/pubmed/25981303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2015.05.013
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