Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors

Lignende værker

• Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists
  af: Booe, Jason M., et al.
  Udgivet: (2018)
• Biochemical characterization of G protein coupling to calcitonin gene–related peptide and adrenomedullin receptors using a native PAGE assay
  af: Roehrkasse, Amanda M., et al.
  Udgivet: (2020)
• Structure–function analyses reveal a triple β-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design
  af: Roehrkasse, Amanda M., et al.
  Udgivet: (2018)
• N-glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity
  af: Lee, Sang-Min, et al.
  Udgivet: (2017)
• Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins
  af: Moad, Heather E, et al.
  Udgivet: (2013)