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Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors
[Image: see text] The calcitonin receptor-like class B G protein-coupled receptor (CLR) mediates adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) functions including vasodilation, cardioprotection, and nociception. Receptor activity-modifying proteins (RAMP1–3) form heterodimers with C...
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| Publicado en: | ACS Pharmacol Transl Sci |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7432658/ https://ncbi.nlm.nih.gov/pubmed/32832875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00031 |
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