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Global individual ancestry using principal components for family data

Studies of human complex diseases and traits associated with candidate genes are potentially vulnerable to bias (confounding) due to population stratification and inbreeding, especially in admixed population. In genome-wide association studies (GWAS) the Principal Components (PCs) method provides a...

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Bibliografische gegevens
Gepubliceerd in:Hum Hered
Hoofdauteurs: de Andrade, Mariza, Ray, Debashree, Pereira, Alexandre C., Soler, Júlia P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583840/
https://ncbi.nlm.nih.gov/pubmed/26159893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381908
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