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Global individual ancestry using principal components for family data

Studies of human complex diseases and traits associated with candidate genes are potentially vulnerable to bias (confounding) due to population stratification and inbreeding, especially in admixed population. In genome-wide association studies (GWAS) the Principal Components (PCs) method provides a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Hered
Main Authors: de Andrade, Mariza, Ray, Debashree, Pereira, Alexandre C., Soler, Júlia P.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583840/
https://ncbi.nlm.nih.gov/pubmed/26159893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381908
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