Linkage analysis using principal components of gene expression data

The goal of this paper is to investigate the effect of using principal components as a data reduction method for expression data in linkage analysis. We used 45 probes normalized using the Affymetrix Global Scaling that had evidence of high heritability to estimate the first 10 principal components...

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Detalhes bibliográficos
Main Authors: Atkinson, Elizabeth J, Fridley, Brooke L, Goode, Ellen L, McDonnell, Shannon K, Liu-Mares, Wen, Rabe, Kari G, Sun, Zhifu, Slager, Susan L, de Andrade, Mariza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367556/
https://ncbi.nlm.nih.gov/pubmed/18466581
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