Assessment of genotype imputation methods

Several methods have been proposed to impute genotypes at untyped markers using observed genotypes and genetic data from a reference panel. We used the Genetic Analysis Workshop 16 rheumatoid arthritis case-control dataset to compare the performance of four of these imputation methods: IMPUTE, MACH,...

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Detalhes bibliográficos
Main Authors: Biernacka, Joanna M, Tang, Rui, Li, Jia, McDonnell, Shannon K, Rabe, Kari G, Sinnwell, Jason P, Rider, David N, de Andrade, Mariza, Goode, Ellen L, Fridley, Brooke L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795949/
https://ncbi.nlm.nih.gov/pubmed/20018042
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