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Fast and robust ancestry prediction using principal component analysis
MOTIVATION: Population stratification (PS) is a major confounder in genome-wide association studies (GWAS) and can lead to false-positive associations. To adjust for PS, principal component analysis (PCA)-based ancestry prediction has been widely used. Simple projection (SP) based on principal compo...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7267814/ https://ncbi.nlm.nih.gov/pubmed/32196066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa152 |
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