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Fast and robust ancestry prediction using principal component analysis

MOTIVATION: Population stratification (PS) is a major confounder in genome-wide association studies (GWAS) and can lead to false-positive associations. To adjust for PS, principal component analysis (PCA)-based ancestry prediction has been widely used. Simple projection (SP) based on principal compo...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Zhang, Daiwei, Dey, Rounak, Lee, Seunggeun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267814/
https://ncbi.nlm.nih.gov/pubmed/32196066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa152
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