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Quantification of Population Structure Using Correlated SNPs by Shrinkage Principal Components

BACKGROUND/AIMS: Association studies using unrelated individuals have become the most popular design for mapping complex traits. One of the major challenges of association mapping is avoiding spurious association due to population stratification. Principal component analysis (PCA) on genome-wide mar...

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Bibliografiska uppgifter
Huvudupphovsmän: Zou, Fei, Lee, Seunggeun, Knowles, Michael R., Wright, Fred A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: S. Karger AG 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912642/
https://ncbi.nlm.nih.gov/pubmed/20413978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288706
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