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Global individual ancestry using principal components for family data

Studies of human complex diseases and traits associated with candidate genes are potentially vulnerable to bias (confounding) due to population stratification and inbreeding, especially in admixed population. In genome-wide association studies (GWAS) the Principal Components (PCs) method provides a...

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Bibliographic Details
Published in:Hum Hered
Main Authors: de Andrade, Mariza, Ray, Debashree, Pereira, Alexandre C., Soler, Júlia P.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583840/
https://ncbi.nlm.nih.gov/pubmed/26159893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381908
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