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Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity
BACKGROUND: Presenting vaccine antigens in particulate form can improve their immunogenicity by enhancing B cell activation. FINDINGS: We describe ferritin-based protein nanoparticles that display multiple copies of native-like HIV-1 envelope glycoprotein trimers (BG505 SOSIP.664). Trimer-bearing na...
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| 出版年: | Retrovirology |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583754/ https://ncbi.nlm.nih.gov/pubmed/26410741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0210-4 |
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